Re: Biggest Metabolic Rate Losers

1

Do we know the dieting did that? Maybe they were heavy in the first place due to unusually slow metabolisms.


Posted by: LizardBreath | Link to this comment | 05- 2-16 1:10 PM
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2

They did a before-and-after metabolic check. I can't tell if the "before" is at the beginning of the show or at the end of the show. The "after" is six years later.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:14 PM
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I don't know how much of the 591.1 deficit would have existed before the show, though. I see what you mean there.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:16 PM
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4

I wonder if the basal metabolic rates are based on data, or some dumb linear extrapolation that someone did based on college kids in 1969. There's no way they'd still be using that for overweight people, I'm going to assume.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:24 PM
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5

I did a crash diet this past fall and lost about 30 lbs in maybe a little over 2 months only to gain back just over 20 of those lbs since December. Now I'm dieting again but not so extremely as before (which was no breakfast, and a handful of almonds for lunch and one felafel sandwich for dinner during weekdays, weekends I ate more or less what I wanted to).


Posted by: Barry Freed | Link to this comment | 05- 2-16 1:25 PM
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6
When the show began, the contestants, though hugely overweight, had normal metabolisms for their size

Posted by: ogged | Link to this comment | 05- 2-16 1:29 PM
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7

And fuck me if I have to eat even less than normal forever when I get to my target weight. This is depressing news.


Posted by: Barry Freed | Link to this comment | 05- 2-16 1:30 PM
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8

6: thanks! And of course, most of the are back at their pre-show weights, with 500 fewer calories to spare.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:35 PM
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9

Think how low your grocery bill will be!


Posted by: ogged | Link to this comment | 05- 2-16 1:36 PM
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10

Slowing of metabolism is an impressive survival mechanism in times of food scarcity. But what I've never understood is what is lost when this mechanism is triggered? Are strength or endurance compromised when metabolism is slowed? I.e. what is the benefit to the human organism of having the faster baseline metabolism during normal times of food availability?


Posted by: urple | Link to this comment | 05- 2-16 1:47 PM
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11

Wait, is this study suggesting that periods of food scarcity actually slow the metabolism permanently?


Posted by: urple | Link to this comment | 05- 2-16 1:49 PM
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12

9: I have considered going on an extreme (yet healthy) grocery-budget diet to see what would happen. I imagine the shocking result would be that I'd become constantly hungry and bitchy, and less productive. But I do spend a fortune on food, so it might still be worth it.


Posted by: lurid keyaki | Link to this comment | 05- 2-16 1:52 PM
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13

I've had pretty large pregnancy-related swings over the past six years, and mostly it has driven home the point of how you can only nudge the needle a teeny bit. Or how I can. Since I stopped nursing for the last time, my appetite has plummeted. It's dramatic.

I actually think that it's not nursing, but the hormone replacement therapy post-hysterectomy. I have a secret theory that my estrogen levels had dropped over all the pregnancies and now they're artificially up to my 20s levels.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:53 PM
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14

11: Yep. Or at least 6 years out.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 1:54 PM
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15

Over the years I have learned just two things about losing weight. 1) In order to lose weight, you have to be hungry a lot. 2) It's easier to be hungry if you eschew grains completely.

I think 1 is true for everybody, and 2 is true for a lot of people. Where's my book deal?


Posted by: ogged | Link to this comment | 05- 2-16 2:01 PM
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16

My dad likes feeling hungry because that's how he knows he isn't gaining weight.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 2:08 PM
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17

I feel like I've left this comment before, which is strange, but I don't actually mind feeling hungry, even quite hungry, if I can focus all my attention on obtaining food. E.g., if I'm hiking and out of food, and won't be able to eat anything until I'm back at camp, walking back to camp is not unpleasant, even if I'm quite hungry. Or if I'm planning to catch and eat fish for dinner, and I'm having a hard time of it, but I can just keep trying. (Or even if I eventually give up and go to bed hungry, planning to try again in the morning.) None of those bother me much. I'm sure it would start to bother me if I ever had to go without food for an extended period, but I've never been in that situation.

But, if I'm hungry and anyone expects me to do anything at all other than figure out when/where/how I'm going to get some food, that's very unpleasant.


Posted by: urple | Link to this comment | 05- 2-16 2:35 PM
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Also if I'm very hungry and don't have anything to eat, and you're around me eating food that smells good, I will literally be tempted to kill you and take your food. It's a temptation I will probably resist, but it's a real temptation.


Posted by: urple | Link to this comment | 05- 2-16 2:38 PM
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19

14: that makes me think the baseline "normal" measurement is inaccurate. How were the baselines developed?


Posted by: urple | Link to this comment | 05- 2-16 2:40 PM
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20

Well, fuck fuck fuck.

I'm dieting again. Mostly fasting, the way I do, a piece of meat and salad once a day. Maybe a slice of cheese and a little fruit at breakfast and bedtime. A drop of 2000-3000 calories a day. Or more.

I don't necessarily get "hungry" I am not even sure what that means. I have always been able to fast. Doesn't mean I'm happy or don't think of food, but I seem to be able to control my cravings.

But yeah, 15.1. Carbs is heroin, and I buy a box of oatmeal cookies and I just can't stop. Feels so good, don't know if it is physical or psychological.

Why You Shouldn't Exercise To Lose Weight Vox, April 28

But we knew this already. When I get down 10-20 pounds, I will start walking, working, free weights.


Posted by: bob mcmanus | Link to this comment | 05- 2-16 2:43 PM
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20: I did have some basic problems with the Vox article in 20, similar to the problems people are having with the OP. The answer might be in basal metabolic rate, but I though they understood it.

Wait, what calorie intake remains same, exercise doubles, and no change in weight? WTF? kinda problem.


Posted by: bob mcmanus | Link to this comment | 05- 2-16 2:51 PM
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22

From the Vox, scroll to point 7

Researchers have discovered a phenomenon called "metabolic compensation," whereby, as people either expend more energy through physical activity or lose weight, their basal metabolic rate slows down.

"The more you stress your body, we think there are changes physiologically -- compensatory mechanisms that change given the level of exercise you're pushing yourself at," said Loyola University exercise physiologist Lara Dugas. In other words, our bodies may actively fight our efforts to lose weight.


Posted by: bob mcmanus | Link to this comment | 05- 2-16 2:53 PM
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What I find most amazing about this is that this implies there are 600 calories per day of efficiency gains to be had. In other words, their body was so inefficient that it can burn 600 calories per day less and still function normally. I would have thought that would be a no go evolutionarily.

Like heebie, I'd like to see the details on how the calculated the expected basal metabolic rate for these folks both before and after.


Posted by: F | Link to this comment | 05- 2-16 3:29 PM
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24

I'm about to go eat at Applebees, so I'm clearly past caring.


Posted by: Moby Hick | Link to this comment | 05- 2-16 3:38 PM
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25

19 is the same question I had when I wrote 4.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 3:45 PM
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26

From the paper: "The predicted RMR [resting metabolic rate] was obtained using a linear regression equation developed using baseline data on body composition, age, and sex in the full 16-person cohort"

So they used a small sample of morbidly obese people to develop their regression, then found that after they lost a bunch of weight their RMR deviated from that regression.


Posted by: F | Link to this comment | 05- 2-16 4:02 PM
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26: How could they have obtained a regression to predict RMR for the cohort based on RMR data for that same cohort? I may be misreading you, but that sounds to me like there was another dataset somewhere correlating RMR with those factors, and they plugged in the cohort's factors against the relevant coefficients.


Posted by: Minivet | Link to this comment | 05- 2-16 4:08 PM
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28

No, they took the RMR data for the cohort at the beginning of the show, obtained a regression from it, then used that regression to predict RMR at the end of the show and 6 years later.


Posted by: F | Link to this comment | 05- 2-16 4:14 PM
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"Contrary to expectations, the degree of metabolic adaptation at the end of the competition was not associated with weight regain, but those with greater long-term weight loss also had greater ongoing metabolic slowing."


Posted by: F | Link to this comment | 05- 2-16 4:18 PM
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Oh, I see.

I don't see how you can do a multivariate regression of any significance at all when n=16, but they say they got results similar to other published studies, so who knows.


Posted by: Minivet | Link to this comment | 05- 2-16 4:34 PM
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31

Hm. This effect seems to have been known for a long time (since at least 1990). One older explanation for the phenomenon is that the regression coefficients for fat-free mass and fat mass are mis-estimated because they compensate. Specifically, fat mass burns more calories per kg than the authors regression estimated, mostly because fat-free mass in obese individuals burns less calories per kg than in lean individuals. So the loss of all that fat mass, which is actually burning more calories than the authors think, causes a big drop in metabolic rate.


Posted by: F | Link to this comment | 05- 2-16 5:16 PM
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Wait, are they being compared to other people of their same size? Or just to a model prediction of their metabolic rate at the new size?

Some of them gained back all their weight, making it an accurate self-comparison.


Posted by: heebie-geebie | Link to this comment | 05- 2-16 5:33 PM
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33

Applebees wasn't that bad.


Posted by: Moby Hick | Link to this comment | 05- 2-16 5:40 PM
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34

I'm thinking about eating a tin of Vienna sausages.


Posted by: Spike | Link to this comment | 05- 2-16 6:06 PM
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35

I was told there was going to be no math.


Posted by: will | Link to this comment | 05- 2-16 6:13 PM
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36

Linear regression is hardly any math at all.


Posted by: Moby Hick | Link to this comment | 05- 2-16 7:33 PM
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37

They took the original obese people and developed a model for their metabolic rate based age, sex, fat-free mass, and fat mass. Then they remeasured those things after they lost the weight, and once more 6 years later after many had gained the weight back. The model said they should have much larger metabolic rates than they actually had at both subsequent points.

They aren't strictly self-comparisons because the model is based on the whole group and the ratio of fat-free mass and fat mass had changed. They didn't publish self-comparisons.

Of the 14 people, 4 basically regained all the weight, and 9 kept off a substantial proportion (roughly half). One went on to lose more weight.

If the model is off, and underestimates the amount of energy that fat mass burns, it would explain some (but not all) of the discrepancy.


Posted by: F | Link to this comment | 05- 2-16 7:38 PM
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38

How did they account for the correlation of multiple time points from the same individual? That's usually some good math.


Posted by: Moby Hick | Link to this comment | 05- 2-16 8:21 PM
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39

They didn't, as far as I can tell.


Posted by: F | Link to this comment | 05- 2-16 9:15 PM
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40

Then they suck.


Posted by: Moby Hick | Link to this comment | 05- 2-16 9:31 PM
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41

17.1: What about when you are splitting open rotten logs to get the grubs out and eat them?


Posted by: Natilo Paennim | Link to this comment | 05- 2-16 9:36 PM
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42

I did a half-assed version of the 5-2 diet a couple of years ago, lost 1/7 of my body-weight over a month or two, and have kept it off with nary a thought since.


Posted by: One of Many | Link to this comment | 05- 2-16 9:48 PM
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43

I know that BMR isn't a useful number for me. I've not been actively dieting recently, but every time I do, I need to go many hundreds of kcal per day under my predicted BMR to even begin to lose weight. That's not under BMR + a calculated extra intake for activity level, but under BMR simpliciter. I've always assumed that that is a by product of the thyroid.

I had a thyroid tumour about 9 years ago, and have struggled much more than I used to to keep weight off, even though I am prescribed thyroid medication. Pre-thyroid tumour, my stable weight was about 40lbs lower than my current stable weight, and I always found it relatively easy to lose weight via cutting food intake somewhat, or increasing activity somewhat. I wasn't skinny, and my weight fluctuated a bit, but dropping it whenever it crept too high wasn't that hard. These days, I lead a more sedentary lifestyle -- long car commute, versus previously a bike/walk commute -- but there definitely seems to be a core metabolic change, too.


Posted by: nattarGcM ttaM | Link to this comment | 05- 3-16 2:54 AM
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44

Being hungry makes me incredibly snappy and short-tempered. I'll settle for being nice-ish and overweight.


Posted by: Parenthetical | Link to this comment | 05- 3-16 5:24 AM
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45

I have a family reunion at the end of the month. It's probably wiser to just tell myself that no matter what I do, I'm going to look hideous next to my selfie-curating elite-college cousins in their late teens and early 20s, but a crash diet sounds awfully appealing. (I don't know how it would work and have never tried. I've long thought I sort of broke my metabolism with eight years of anorexia and then after I had my gall bladder out I really gained. But I think that's mostly making excuses for being older and sedentary and not eating well enough because it seems like so much work.)


Posted by: Thorn | Link to this comment | 05- 3-16 1:42 PM
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46

Whatever you do, you won't look hideous. You've posted pictures to FB in the last couple of weeks that looked great.


Posted by: LizardBreath | Link to this comment | 05- 3-16 1:48 PM
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47

What if she turned her gall bladder into a hat?


Posted by: Moby Hick | Link to this comment | 05- 3-16 1:50 PM
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48

I'm probably too happy that none of my younger cousins got into better colleges than I did.


Posted by: Moby Hick | Link to this comment | 05- 3-16 1:54 PM
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49

Bunch of social climbers.


Posted by: Moby Hick | Link to this comment | 05- 3-16 1:57 PM
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50

I don't even HAVE a gall bladder, Mobes!

And seriously, no one is going to be saying "here's the first-year at Cornell and here's the one pushing 40 as a single mother!" (They'll be assuming I'm my mother, as usual, I'm sure.)


Posted by: Thorn | Link to this comment | 05- 3-16 2:00 PM
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51

I thought they let you keep it, for using as a hat or if you wanted to be buried in a Jewish cemetery.


Posted by: Moby Hick | Link to this comment | 05- 3-16 2:12 PM
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52

There's a woman in the airport here taking a selfie. I'd offer to the the picture for her but I think she's faster than me so I couldn't steal the phone.


Posted by: Moby Hick | Link to this comment | 05- 3-16 2:45 PM
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53

She's giving a speech to Facebook for something she's going to talk to the EPA about, so she probably needs her phone more than I need it.


Posted by: Moby Hick | Link to this comment | 05- 3-16 2:49 PM
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54

Excuses, excuses.


Posted by: Mossy Character | Link to this comment | 05- 3-16 7:51 PM
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